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The While Loop is the most suitable loop structure for an application that requires continual monitoring and responding to data changes. This is because the While Loop is designed to execute its contained code repeatedly as long as a specified condition remains true. In scenarios where ongoing data monitoring is necessary, the While Loop can continuously check for changes in data and react accordingly until explicitly instructed to stop.

This structure allows for the implementation of real-time data handling, ensuring that the application can adapt and respond to new information as it arrives. For example, in applications such as data logging or real-time control systems, the ability to keep the loop running allows for constant input checks and decision-making processes based on the most current datasets.

Other options are less suitable for this use case. A For Loop, for instance, is intended for a predetermined number of iterations, which does not support continuous monitoring as it would exit after reaching its specified limit. An Event Structure is typically used for event-driven programming, responding to user actions or specific data changes, but it does not function as a loop in the traditional sense for continuous operation. The Case Structure provides conditional branching rather than a loop mechanism, making it inappropriate for ongoing data monitoring tasks.